Allgemeine Kiffpflicht

From	Mike Grantz <invalid@invalid.invalid>
Newsgroups	ger.ct
Subject	Allgemeine Kiffpflicht
Date	2022-01-13 12:57 +0100
Organization	A noiseless patient Spider
Message-ID	<srp43h$grm$1@dont-email.me> (permalink)

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https://pubmed.ncbi.nlm.nih.gov/35007072/#heading

Cannabinoids Block Cellular Entry of SARS-CoV-2 and the Emerging Variants

"
Abstract

As a complement to vaccines, small-molecule therapeutic agents are 
needed to treat or prevent infections by severe acute respiratory 
syndrome coronavirus-2 (SARS-CoV-2) and its variants, which cause 
COVID-19. Affinity selection-mass spectrometry was used for the 
discovery of botanical ligands to the SARS-CoV-2 spike protein. 
Cannabinoid acids from hemp (Cannabis sativa) were found to be 
allosteric as well as orthosteric ligands with micromolar affinity for 
the spike protein. In follow-up virus neutralization assays, 
cannabigerolic acid and cannabidiolic acid prevented infection of human 
epithelial cells by a pseudovirus expressing the SARS-CoV-2 spike 
protein and prevented entry of live SARS-CoV-2 into cells. Importantly, 
cannabigerolic acid and cannabidiolic acid were equally effective 
against the SARS-CoV-2 alpha variant B.1.1.7 and the beta variant 
B.1.351. Orally bioavailable and with a long history of safe human use, 
these cannabinoids, isolated or in hemp extracts, have the potential to 
prevent as well as treat infection by SARS-CoV-2.
"

https://pubs.acs.org/doi/10.1021/acs.jnatprod.1c00946

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Allgemeine Kiffpflicht Mike Grantz <invalid@invalid.invalid> - 2022-01-13 12:57 +0100
  Re: Allgemeine Kiffpflicht Matthias Wendt <wendt2@schumann-ga.de> - 2022-01-13 14:44 +0100
    Re: Allgemeine Kiffpflicht Ulf Kutzner <Ulf.Kutzner@web.de> - 2022-01-13 05:51 -0800
      Re: Allgemeine Kiffpflicht Mike Grantz <invalid@invalid.invalid> - 2022-01-13 16:06 +0100
  Re: Allgemeine Kiffpflicht Martin Pochert <pochert.no.spam@gmx.de> - 2022-01-13 15:55 +0100
    Re: Allgemeine Kiffpflicht Georg Gruber <g.gruber_hauwech@gmx.net> - 2022-01-15 11:20 +0100
    Re: Allgemeine Kiffpflicht Hermann Riemann <nospam.ng@hermann-riemann.de> - 2022-01-15 12:03 +0100
      Re: Allgemeine Kiffpflicht Lars Gebauer <lgebauer@live.de> - 2022-01-15 12:18 +0100
      Re: Allgemeine Kiffpflicht Matthias Eißing <meissing@gmx.de> - 2022-01-15 12:16 +0100
        Re: Allgemeine Kiffpflicht Michael Bode <m.g.bode@web.de> - 2022-01-15 13:48 +0100
          Re: Allgemeine Kiffpflicht Michael Bode <m.g.bode@web.de> - 2022-01-15 13:58 +0100
            Re: Allgemeine Kiffpflicht Ulf Kutzner <Ulf.Kutzner@web.de> - 2022-01-15 05:05 -0800
            Re: Allgemeine Kiffpflicht Jörg Tewes <jogi1964@gmx.net> - 2022-01-15 23:53 +0100
              Re: Allgemeine Kiffpflicht Mike Grantz <invalid@invalid.invalid> - 2022-01-16 03:13 +0100
          Re: Allgemeine Kiffpflicht Mike Grantz <invalid@invalid.invalid> - 2022-01-15 16:14 +0100
      Re: Allgemeine Kiffpflicht Martin Pochert <pochert.no.spam@gmx.de> - 2022-01-15 15:00 +0100
        Re: Allgemeine Kiffpflicht Hermann Riemann <nospam.ng@hermann-riemann.de> - 2022-01-15 18:13 +0100
          Re: Allgemeine Kiffpflicht Ulf Kutzner <Ulf.Kutzner@web.de> - 2022-01-15 09:31 -0800
            Re: Allgemeine Kiffpflicht Mike Grantz <invalid@invalid.invalid> - 2022-01-16 03:18 +0100
              Re: Allgemeine Kiffpflicht Ulf Kutzner <Ulf.Kutzner@web.de> - 2022-01-17 05:13 -0800
  Re: Allgemeine Kiffpflicht Mike Grantz <invalid@invalid.invalid> - 2022-01-14 21:32 +0100

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