Re: Aufstand der Aerzte

From	"Dr. Joachim Neudert" <neudert@5sl.org>
Newsgroups	ger.ct
Subject	Re: Aufstand der Aerzte
Date	2021-02-11 19:11 +0100
Message-ID	<s03s05$4cu$1@solani.org> (permalink)
References	<5t602524cfi3f91n3e8%sfroehli@Froehlich.Priv.at>

Show all headers | View raw

Am 11.02.21 um 13:39 schrieb Stefan Froehlich:
> Ich finde auf die Schnelle nicht, wo Joachim einen Aufstand des
> medizinischen Personals prophezeit hat, wenn sie mit dem "billigen
> Dreck" aus England anstatt mit dem "guten Zeug" aus Deutschland
> geimpft werden, aber in Österreich sind wir heute an diesem Punkt
> angekommen: <https://wien.orf.at/stories/3089713/>. Wird sich halt
> eher... blöd auf die Impfbereitschaft der Bevölkerung auswirken,
> wenn sie damit durchkommen.
> 
> Wenn nicht eh alles ganz anders kommt, Tirol hat nämlich gestern
> Abend in einem Anfall von Bauernschläue gefordert, man möge den
> gesamten BioNTech-Impfstoff für Österreich ausschließlich in Tirol
> verimpfen, bis dort Herdenimmunität erreicht sei. Schließlich
> zirkuliere dort die gefährliche südafrikanische Mutation, und
> dagegen wäre man mit AstraZeneka nicht gefeit.
> 
> Noch 2-3 Wochen und idealerweise irgendein Superspreader-Event, dann
> haben wir Bürgerkrieg.
> 
> Servus,
>     Stefan
> 


Vor allem wenn man neueste Daten ansieht:

Pfizer vaccine found to give strong immune response to  *new Covid 
variants*
Study finds patients have strong T-cell response after one jab, and 
second boosts antibody response

https://www.theguardian.com/world/2021/feb/11/pfizer-vaccine-strong-response-new-covid-variants

People who have received two doses of the Pfizer vaccine have been found 
to have strong T-cell responses against the Kent and South African 
variants of Covid, suggesting that the vaccine will continue to protect 
against serious disease in the coming months.

In the first study to test immune responses against the variants 
circulating in populations, researchers found that although antibody 
responses against the new variants were blunted, they may still be high 
enough to protect most people from becoming infected, after a second 
dose of vaccine has been given.

Although previous studies had suggested that antibodies from those 
vaccinated with the Pfizer/BioNTech jab could recognise and neutralise 
viruses carrying some of the individual mutations found in the South 
African and Kent variants – albeit at slightly lower levels compared 
with previous variants – these were tested on engineered viruses rather 
than ones isolated from real patients.

These studies also did not look at T cells, which annihilate 
virus-infected cells and support the production of antibodies. Both 
immune responses help provide lasting protection after vaccination, but 
antibody responses are easier to measure.

William James, a professor of virology at the University of Oxford, and 
his colleagues took blood samples from people who had recovered from 
Covid-19, and health workers who had received either one or two doses of 
the Pfizer/BioNTech vaccine. They also obtained isolates of the B117 and 
B1.351 virus variants first identified in Kent and South Africa, and of 
an older variant similar to those circulating a year ago. Antibodies and 
T cells from the individuals were then tested against these viruses to 
see how well they performed.

The study, which has not yet been reviewed by other scientists, found 
that people’s antibodies were moderately effective against the original 
virus after their first dose of vaccine, less effective against the Kent 
variant, and were unable to neutralise the South African variant.

However, they had strong T-cell responses against all known variants 
after the first jab. “It may not necessarily protect you against 
infection, but it’s very likely that this first dose will make it much 
easier for your immune system to make a good response the next time 
around,” said James. “We think this is why that second dose produces 
such a good strong antibody response, because the T cells are already 
there, ready to react.”

The discovery that people who have recovered from Covid-19 and those who 
have received at least one dose of vaccine possess T cells capable of 
responding to the new variants is encouraging, because it suggests the T 
cells are recognising different regions of the spike protein to the 
antibodies. It could imply they will be more resilient to future 
variants. “It doesn’t promise you won’t get ill from the new variants, 
but it does suggest there’s something to work from and that your immune 
system can respond to them,” said James.

People’s antibody responses were also boosted by the second Pfizer jab. 
“In more than 90% of cases, the antibodies that people are generating 
after the second dose are up at the sort of level that neutralises the 
virus and which we would expect to protect them from infection,” said 
James. “We’re pretty confident that they’ll be protected from infection 
by the South African strain and the Kent strain, as well as the 
[original] strain of the virus.

“This virus hasn’t finished evolving, but I think that as long as the 
vaccines get rolled out, and people get those second doses, we’re going 
to be in a much better position by the summer than we are now,” said James.

Deborah Dunn-Walters, a professor of immunology at the University of 
Surrey, said: “It does look like good news and suggests it is really 
important that people go back for their second dose of vaccine.”

Prof Paul Morgan, the director of the Systems Immunity Research 
Institute at Cardiff University, said: “I was supportive of the 
pragmatic decision to delay second doses to get more people immunised as 
quickly as possible and I still am. However, this work shows that the 
broad immune response needed to deal with current and future variants of 
concern is really dependent on boosting.

“I think that the message is to get the second doses going as soon as 
possible – perhaps as soon as the high-risk groups have all had first 
doses, which means pretty soon.”

The findings also shed light on the risk of reinfection with new 
variants for people who have already recovered from Covid-19. T-cell 
activity was detected in all of them, but there was widespread variation 
in their antibody responses. “In the best responders, you could still 
measure some neutralisation against even the South African strain, but 
those who had rather weaker responses had no neutralisation activity,” 
said James. “It shows it’s really important to get vaccinated, even if 
you’ve think you’ve recovered from the virus.”

Although they did not look at immune responses from people injected with 
other types of Covid-19 vaccines, James suspects they will generate 
similar immune responses.

Morgan said: “The findings add to the growing confidence that the 
current vaccines will have a large impact on the course of the pandemic, 
whether by completely protecting from or markedly ameliorating disease.”

Back to ger.ct | Previous | Next — Next in thread | Find similar | Unroll thread

Thread

Re: Aufstand der Aerzte "Dr. Joachim Neudert" <neudert@5sl.org> - 2021-02-11 19:11 +0100
  Re: Aufstand der Aerzte Dr. Joachim Neudert <neudert@5sl.org> - 2021-02-11 20:56 +0000
    Re: Aufstand der Aerzte Hergen Lehmann <hlehmann.expires.5-11@snafu.de> - 2021-02-11 22:44 +0100
      Re: Aufstand der Aerzte Fidel Sebastián Hunrichse-Lara <Fidel-Sebastian_Hunrichse_Lara@b.maus.de> - 2021-02-11 17:26 -0500
      Re: Aufstand der Aerzte Hergen Lehmann <hlehmann.expires.5-11@snafu.de> - 2021-02-12 00:02 +0100
      Re: Aufstand der Aerzte Martin Ebert <mx300@gmx.net> - 2021-02-12 03:25 +0100
        Re: Aufstand der Aerzte Lars Gebauer <lgebauer@live.de> - 2021-02-12 09:55 +0100
      Re: Aufstand der Aerzte Dr. Joachim Neudert <neudert@5sl.org> - 2021-02-12 05:24 +0000
        Re: Aufstand der Aerzte "Dr. Joachim Neudert" <neudert@5sl.org> - 2021-02-12 08:00 +0100
          Re: Aufstand der Aerzte "Dr. Joachim Neudert" <neudert@5sl.org> - 2021-02-12 08:16 +0100
            Re: Aufstand der Aerzte "Dr. Joachim Neudert" <neudert@5sl.org> - 2021-02-12 08:40 +0100
        Re: Aufstand der Aerzte Ulf Kutzner <Ulf.Kutzner@web.de> - 2021-02-11 23:26 -0800
          Re: Aufstand der Aerzte Lars Gebauer <lgebauer@live.de> - 2021-02-12 10:25 +0100
            Re: Aufstand der Aerzte Ulf Kutzner <Ulf.Kutzner@web.de> - 2021-02-12 02:15 -0800
            Re: Aufstand der Aerzte Lars Gebauer <lgebauer@live.de> - 2021-02-12 12:07 +0100
          Re: Aufstand der Aerzte Ulf Kutzner <Ulf.Kutzner@web.de> - 2021-02-12 01:25 -0800
            Re: Aufstand der Aerzte Ulf Kutzner <Ulf.Kutzner@web.de> - 2021-02-12 02:21 -0800
              Re: Aufstand der Aerzte Ulf Kutzner <Ulf.Kutzner@web.de> - 2021-02-12 02:38 -0800
              Re: Aufstand der Aerzte Lars Gebauer <lgebauer@live.de> - 2021-02-12 11:51 +0100
                Re: Aufstand der Aerzte Martin Ebert <mx300@gmx.net> - 2021-02-12 18:44 +0100
                Re: Aufstand der Aerzte Lars Gebauer <lgebauer@live.de> - 2021-02-12 19:06 +0100
                Re: Aufstand der Aerzte Ulf Kutzner <Ulf.Kutzner@web.de> - 2021-02-12 10:13 -0800
                Re: Aufstand der Aerzte spamfalle2@arcor.de (Marc Stibane) - 2021-02-12 22:06 +0100
                Re: Aufstand der Aerzte Dietz Proepper <dietz-usenet@rotfl.franken.de> - 2021-02-13 11:31 +0100
            Re: Aufstand der Aerzte Martin Ebert <mx300@gmx.net> - 2021-02-12 18:43 +0100
              Re: Aufstand der Aerzte Peter Veith <veith@snafu.de> - 2021-02-12 19:46 +0100
                Re: Aufstand der Aerzte Ulf Kutzner <Ulf.Kutzner@web.de> - 2021-02-12 10:53 -0800
                Re: Aufstand der Aerzte Martin Ebert <mx300@gmx.net> - 2021-02-12 21:45 +0100
              Re: Aufstand der Aerzte Diedrich Ehlerding <diedrich.ehlerding@t-online.de> - 2021-02-12 21:41 +0100
              Re: Aufstand der Aerzte Ulf Kutzner <Ulf.Kutzner@web.de> - 2021-02-12 13:07 -0800
        Re: Aufstand der Aerzte "Dr. Joachim Neudert" <neudert@5sl.org> - 2021-02-12 09:09 +0100
          Re: Aufstand der Aerzte Ulf Kutzner <Ulf.Kutzner@web.de> - 2021-02-12 00:40 -0800
        Re: Aufstand der Aerzte Lars Gebauer <lgebauer@live.de> - 2021-02-12 09:30 +0100
          Re: Aufstand der Aerzte "Dr. Joachim Neudert" <neudert@5sl.org> - 2021-02-12 09:34 +0100
      Re: Aufstand der Aerzte Lars Gebauer <lgebauer@live.de> - 2021-02-12 10:46 +0100
        Re: Aufstand der Aerzte "Dr. Joachim Neudert" <neudert@5sl.org> - 2021-02-12 10:53 +0100
          Re: Aufstand der Aerzte Lars Gebauer <lgebauer@live.de> - 2021-02-12 11:42 +0100
            Re: Aufstand der Aerzte "Dr. Joachim Neudert" <neudert@5sl.org> - 2021-02-12 12:07 +0100
              Re: Aufstand der Aerzte Lars Gebauer <lgebauer@live.de> - 2021-02-12 12:20 +0100
                Re: Aufstand der Aerzte "Dr. Joachim Neudert" <neudert@5sl.org> - 2021-02-12 12:27 +0100
                Re: Aufstand der Aerzte Lars Gebauer <lgebauer@live.de> - 2021-02-12 12:40 +0100
                Re: Aufstand der Aerzte "Dr. Joachim Neudert" <neudert@5sl.org> - 2021-02-12 12:42 +0100
                Re: Aufstand der Aerzte Lars Gebauer <lgebauer@live.de> - 2021-02-12 12:53 +0100
      Re: Aufstand der Aerzte "herwig...@t-online.de" <herwig.huener@t-online.de> - 2021-02-12 06:31 -0800
    Re: Aufstand der Aerzte Ulf Kutzner <Ulf.Kutzner@web.de> - 2021-02-11 14:10 -0800
    Re: Aufstand der Aerzte Dr. Joachim Neudert <neudert@5sl.org> - 2021-02-12 06:09 +0000
      Re: Aufstand der Aerzte Dr. Joachim Neudert <neudert@5sl.org> - 2021-02-12 06:19 +0000
        Re: Aufstand der Aerzte Ulf Kutzner <Ulf.Kutzner@web.de> - 2021-02-11 23:22 -0800
      Re: Aufstand der Aerzte Ulf Kutzner <Ulf.Kutzner@web.de> - 2021-02-11 23:20 -0800
      Re: Aufstand der Aerzte Fidel Sebastián Hunrichse-Lara <Fidel-Sebastian_Hunrichse_Lara@b.maus.de> - 2021-02-12 07:49 -0500
    Re: Aufstand der Aerzte Lars Gebauer <lgebauer@live.de> - 2021-02-12 10:52 +0100
      Re: Aufstand der Aerzte "Dr. Joachim Neudert" <neudert@5sl.org> - 2021-02-12 10:55 +0100
  Re: Aufstand der Aerzte Fidel Sebastián Hunrichse-Lara <Fidel-Sebastian_Hunrichse_Lara@b.maus.de> - 2021-02-13 11:46 -0500

csiph-web