Re: code for 32/64 bit strtoul strtol strtoull strtoll

From	Keith Thompson <kst-u@mib.org>
Newsgroups	comp.lang.c
Subject	Re: code for 32/64 bit strtoul strtol strtoull strtoll
Date	2015-03-31 17:00 -0700
Organization	None to speak of
Message-ID	<87mw2siup6.fsf@kst-u.example.com> (permalink)
References	(9 earlier) <mfer4g$t2o$1@dont-email.me> <551AF2FC.8080802@verizon.net> <mfeu1b$ulk$1@speranza.aioe.org> <551B09BE.5080109@verizon.net> <76ef08ab-2319-4b5f-a994-5d80e0604aa5@googlegroups.com>

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Malcolm McLean <malcolm.mclean5@btinternet.com> writes:
> On Tuesday, March 31, 2015 at 9:55:38 PM UTC+1, James Kuyper wrote:
>> Given that ribosomes translate base pair triplets into amino acids,
>> there might be some value in wasting a little space encoding only three
>> base pairs per byte. On the other hand, since a triplet can start with
>> any given base pair, depending upon where the ribosome starts reading,
>> that might not be worthwhile (there are particular base pair sequences
>> that serve to align the ribosomes to the "correct" starting point for a
>> given gene - there's also some cases where those alignment clues are
>> missing, where  multiple different proteins are encoded by the same DNA
>> sequence, depending upon where you start).
>> 
> There might be a case of an overlapping gene with a different frame
> somewhere, but it's extremely rare.
> If you start transcribing RNA out of frame, it's like taking ascii
> text and shifting everything along by two bits - the result has to
> be nonsense, it won't form a functional protein but just a blob
> with no particular secondary or tertiary structure.

According to
    http://www.pandasthumb.org/archives/2007/10/konstantin-b-ze.html
these are called "alternate reading frames".

Relevance to C (or at least to programming): This could imply that a
base-64 representation of DNA sequences, using 6 bits for each sequence
of 3 base pairs, is not always adequate.  You need base 4 to allow for
1- or 2-base offsets.  Even without alternate reading frames, you still
need to figure out one of three possible offsets (and one of two
directions) to determine where the boundaries are and what, if anything,
the gene encodes.

-- 
Keith Thompson (The_Other_Keith) kst-u@mib.org  <http://www.ghoti.net/~kst>
Working, but not speaking, for JetHead Development, Inc.
"We must do something.  This is something.  Therefore, we must do this."
    -- Antony Jay and Jonathan Lynn, "Yes Minister"

Thread

code for 32/64 bit strtoul strtol strtoull strtoll jacob navia <jacob@jacob.remcomp.fr> - 2015-03-29 17:33 +0200
  code for 32/64 bit strtoul strtol strtoull strtoll asetofsymbols@gmail.com - 2015-03-29 09:22 -0700
    Re: code for 32/64 bit strtoul strtol strtoull strtoll Barry Schwarz <schwarzb@dqel.com> - 2015-03-29 15:12 -0700
      Re: code for 32/64 bit strtoul strtol strtoull strtoll asetofsymbols@gmail.com - 2015-03-29 23:07 -0700
  Re: code for 32/64 bit strtoul strtol strtoull strtoll Barry Schwarz <schwarzb@dqel.com> - 2015-03-29 09:44 -0700
    Re: code for 32/64 bit strtoul strtol strtoull strtoll jacob navia <jacob@jacob.remcomp.fr> - 2015-03-29 19:05 +0200
      Re: code for 32/64 bit strtoul strtol strtoull strtoll Keith Thompson <kst-u@mib.org> - 2015-03-29 12:15 -0700
  Re: code for 32/64 bit strtoul strtol strtoull strtoll Ben Bacarisse <ben.usenet@bsb.me.uk> - 2015-03-30 02:01 +0100
    Re: code for 32/64 bit strtoul strtol strtoull strtoll Keith Thompson <kst-u@mib.org> - 2015-03-29 19:48 -0700
      Re: code for 32/64 bit strtoul strtol strtoull strtoll Barry Schwarz <schwarzb@dqel.com> - 2015-03-29 22:08 -0700
        Re: code for 32/64 bit strtoul strtol strtoull strtoll Ben Bacarisse <ben.usenet@bsb.me.uk> - 2015-03-30 12:44 +0100
          Re: code for 32/64 bit strtoul strtol strtoull strtoll Barry Schwarz <schwarzb@dqel.com> - 2015-03-30 09:04 -0700
            Re: code for 32/64 bit strtoul strtol strtoull strtoll Ben Bacarisse <ben.usenet@bsb.me.uk> - 2015-03-30 21:00 +0100
        Re: code for 32/64 bit strtoul strtol strtoull strtoll Keith Thompson <kst-u@mib.org> - 2015-03-30 08:24 -0700
      Re: code for 32/64 bit strtoul strtol strtoull strtoll Tim Rentsch <txr@alumni.caltech.edu> - 2015-03-30 07:21 -0700
  Re: code for 32/64 bit strtoul strtol strtoull strtoll Ian Collins <ian-news@hotmail.com> - 2015-03-30 18:02 +1300
    Re: code for 32/64 bit strtoul strtol strtoull strtoll Richard Heathfield <rjh@cpax.org.uk> - 2015-03-30 08:03 +0100
      Re: code for 32/64 bit strtoul strtol strtoull strtoll Ian Collins <ian-news@hotmail.com> - 2015-03-30 20:33 +1300
        Re: code for 32/64 bit strtoul strtol strtoull strtoll Ian Collins <ian-news@hotmail.com> - 2015-03-30 20:35 +1300
  Re: code for 32/64 bit strtoul strtol strtoull strtoll Tim Rentsch <txr@alumni.caltech.edu> - 2015-03-30 07:27 -0700
  Re: code for 32/64 bit strtoul strtol strtoull strtoll Keith Thompson <kst-u@mib.org> - 2015-03-30 09:08 -0700
  Re: code for 32/64 bit strtoul strtol strtoull strtoll Keith Thompson <kst-u@mib.org> - 2015-03-30 09:29 -0700
  Re: code for 32/64 bit strtoul strtol strtoull strtoll Robert Wessel <robertwessel2@yahoo.com> - 2015-03-30 15:16 -0500
    Re: code for 32/64 bit strtoul strtol strtoull strtoll jacob navia <jacob@jacob.remcomp.fr> - 2015-03-31 00:15 +0200
      Re: code for 32/64 bit strtoul strtol strtoull strtoll Robert Wessel <robertwessel2@yahoo.com> - 2015-03-31 01:42 -0500
    Re: code for 32/64 bit strtoul strtol strtoull strtoll Bartc <bc@freeuk.com> - 2015-03-30 23:39 +0100
      Re: code for 32/64 bit strtoul strtol strtoull strtoll Robert Wessel <robertwessel2@yahoo.com> - 2015-03-31 01:44 -0500
        Re: code for 32/64 bit strtoul strtol strtoull strtoll Bartc <bc@freeuk.com> - 2015-03-31 13:01 +0100
          Re: code for 32/64 bit strtoul strtol strtoull strtoll Malcolm McLean <malcolm.mclean5@btinternet.com> - 2015-03-31 05:13 -0700
          Re: code for 32/64 bit strtoul strtol strtoull strtoll Keith Thompson <kst-u@mib.org> - 2015-03-31 08:06 -0700
            Re: code for 32/64 bit strtoul strtol strtoull strtoll Keith Thompson <kst-u@mib.org> - 2015-03-31 08:26 -0700
            Re: code for 32/64 bit strtoul strtol strtoull strtoll Richard Heathfield <rjh@cpax.org.uk> - 2015-03-31 16:40 +0100
              Re: code for 32/64 bit strtoul strtol strtoull strtoll Malcolm McLean <malcolm.mclean5@btinternet.com> - 2015-03-31 09:39 -0700
              Re: code for 32/64 bit strtoul strtol strtoull strtoll Kaz Kylheku <kaz@kylheku.com> - 2015-03-31 18:22 +0000
                Re: code for 32/64 bit strtoul strtol strtoull strtoll Richard Heathfield <rjh@cpax.org.uk> - 2015-03-31 19:36 +0100
                Re: code for 32/64 bit strtoul strtol strtoull strtoll Keith Thompson <kst-u@mib.org> - 2015-03-31 12:11 -0700
                Re: code for 32/64 bit strtoul strtol strtoull strtoll Kaz Kylheku <kaz@kylheku.com> - 2015-03-31 19:23 +0000
            Re: code for 32/64 bit strtoul strtol strtoull strtoll Bartc <bc@freeuk.com> - 2015-03-31 16:52 +0100
              Re: code for 32/64 bit strtoul strtol strtoull strtoll glen herrmannsfeldt <gah@ugcs.caltech.edu> - 2015-03-31 17:54 +0000
                Re: code for 32/64 bit strtoul strtol strtoull strtoll raltbos@xs4all.nl (Richard Bos) - 2015-03-31 18:51 +0000
                Re: code for 32/64 bit strtoul strtol strtoull strtoll Richard Heathfield <rjh@cpax.org.uk> - 2015-03-31 20:05 +0100
                Re: code for 32/64 bit strtoul strtol strtoull strtoll James Kuyper <jameskuyper@verizon.net> - 2015-03-31 15:18 -0400
                Re: code for 32/64 bit strtoul strtol strtoull strtoll Richard Heathfield <rjh@cpax.org.uk> - 2015-03-31 20:49 +0100
                Re: code for 32/64 bit strtoul strtol strtoull strtoll Malcolm McLean <malcolm.mclean5@btinternet.com> - 2015-03-31 13:06 -0700
                Re: code for 32/64 bit strtoul strtol strtoull strtoll raltbos@xs4all.nl (Richard Bos) - 2015-04-06 13:03 +0000
                Re: code for 32/64 bit strtoul strtol strtoull strtoll Bartc <bc@freeuk.com> - 2015-04-06 14:27 +0100
                Re: code for 32/64 bit strtoul strtol strtoull strtoll Richard Heathfield <rjh@cpax.org.uk> - 2015-04-06 17:01 +0100
                Re: code for 32/64 bit strtoul strtol strtoull strtoll Malcolm McLean <malcolm.mclean5@btinternet.com> - 2015-04-06 11:25 -0700
                Re: code for 32/64 bit strtoul strtol strtoull strtoll James Kuyper <jameskuyper@verizon.net> - 2015-04-06 23:34 -0400
                Re: code for 32/64 bit strtoul strtol strtoull strtoll glen herrmannsfeldt <gah@ugcs.caltech.edu> - 2015-04-07 03:46 +0000
                Re: code for 32/64 bit strtoul strtol strtoull strtoll James Kuyper <jameskuyper@verizon.net> - 2015-04-08 11:05 -0400
                Re: code for 32/64 bit strtoul strtol strtoull strtoll Malcolm McLean <malcolm.mclean5@btinternet.com> - 2015-04-08 08:31 -0700
                Re: code for 32/64 bit strtoul strtol strtoull strtoll glen herrmannsfeldt <gah@ugcs.caltech.edu> - 2015-03-31 19:54 +0000
                Re: code for 32/64 bit strtoul strtol strtoull strtoll James Kuyper <jameskuyper@verizon.net> - 2015-03-31 16:55 -0400
                Re: code for 32/64 bit strtoul strtol strtoull strtoll Bartc <bc@freeuk.com> - 2015-03-31 22:20 +0100
                Re: code for 32/64 bit strtoul strtol strtoull strtoll Keith Thompson <kst-u@mib.org> - 2015-03-31 14:36 -0700
                Re: code for 32/64 bit strtoul strtol strtoull strtoll Malcolm McLean <malcolm.mclean5@btinternet.com> - 2015-03-31 14:55 -0700
                Re: code for 32/64 bit strtoul strtol strtoull strtoll Keith Thompson <kst-u@mib.org> - 2015-03-31 17:00 -0700
                Re: code for 32/64 bit strtoul strtol strtoull strtoll Bartc <bc@freeuk.com> - 2015-04-01 01:24 +0100
                Re: code for 32/64 bit strtoul strtol strtoull strtoll James Kuyper <jameskuyper@verizon.net> - 2015-03-31 23:33 -0400
                Re: code for 32/64 bit strtoul strtol strtoull strtoll Richard Heathfield <rjh@cpax.org.uk> - 2015-04-01 04:42 +0100
                Re: code for 32/64 bit strtoul strtol strtoull strtoll Bartc <bc@freeuk.com> - 2015-03-31 20:26 +0100
            Re: code for 32/64 bit strtoul strtol strtoull strtoll Ian Collins <ian-news@hotmail.com> - 2015-04-01 10:33 +1300
              Re: code for 32/64 bit strtoul strtol strtoull strtoll Robert Wessel <robertwessel2@yahoo.com> - 2015-04-01 04:33 -0500
                Re: code for 32/64 bit strtoul strtol strtoull strtoll Bartc <bc@freeuk.com> - 2015-04-01 12:43 +0100
                Re: code for 32/64 bit strtoul strtol strtoull strtoll Robert Wessel <robertwessel2@yahoo.com> - 2015-04-02 01:02 -0500
                Re: code for 32/64 bit strtoul strtol strtoull strtoll asetofsymbols@gmail.com - 2015-04-01 23:57 -0700
                Re: code for 32/64 bit strtoul strtol strtoull strtoll Robert Wessel <robertwessel2@yahoo.com> - 2015-04-03 00:29 -0500
                Re: code for 32/64 bit strtoul strtol strtoull strtoll Malcolm McLean <malcolm.mclean5@btinternet.com> - 2015-04-02 09:01 -0700
                Re: code for 32/64 bit strtoul strtol strtoull strtoll Keith Thompson <kst-u@mib.org> - 2015-04-02 14:30 -0700
                Re: code for 32/64 bit strtoul strtol strtoull strtoll Robert Wessel <robertwessel2@yahoo.com> - 2015-04-03 00:39 -0500
                Re: code for 32/64 bit strtoul strtol strtoull strtoll glen herrmannsfeldt <gah@ugcs.caltech.edu> - 2015-04-01 15:55 +0000

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