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From: Peter Otten <__peter__@web.de>
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Subject: Re: new to python, help please !!
Date: Thu, 12 Nov 2015 15:56:40 +0100
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Tim Chase wrote:

>   with open("file1.md5") as a, open("file2.md5") as b:
>     for s1, s2 in zip(a, b):
>       if s1 != s2:
>         print("Files differ")

Note that this will not detect extra lines in one of the files.
I recommend that you use itertools.zip_longest (izip_longest in Python 2) 
instead of the built-in zip().